生化危机 2，在日本被称为生化危机 2（日文：バイオハザード2 Hepburn: Baiohazādo Tsū?），是 1998 年最初为 PlayStation 发布的生存恐怖视频游戏。由 Capcom 开发，作为《生化危机》系列的第二部，它的故事发生在第一部游戏《生化危机》事件发生两个月后。故事发生在美国社区浣熊市，那里的居民被安布雷拉制药公司开发的生物武器 T 病毒变成了僵尸。两位主角莱昂·S·肯尼迪（Leon S. Kennedy）和克莱尔·雷德菲尔德（Claire Redfield）在逃离城市的过程中遇到了其他幸存者，并遇到了更强大的 G 病毒的变异创造者威廉·伯金（William Birkin）。
Resident Evil 2, known in Japan as Biohazard 2 (Japanese: バイオハザード2 Hepburn: Baiohazādo Tsū?), is a 1998 survival horror video game originally released for the PlayStation. Developed by Capcom as the second installment in the Resident Evil series, its story takes place two months after the events of the first game, Resident Evil. It is set in Raccoon City, an American community whose residents have been transformed into zombies by the T-virus, a biological weapon developed by the pharmaceutical company Umbrella. In their escape from the city, the two protagonists, Leon S. Kennedy and Claire Redfield, encounter other survivors, and are confronted by William Birkin, the mutated creator of the even more powerful G-virus.